Fortnite takes place in the same universe as The Powerpuff Girls. Now, before you start ranting, hear me out. Fortnite has Thanos in it. Thanos is in Marvel Vs. Capcom Infinite. Mega Man X is in Marvel vs. Capcom, and Mega Man X in the same universe as Mega Man, since Dr. Light created both of them. Mega Man is in Smash Bros, and so is Pac Man, who appears in Wreck-it Ralph. One scene in Wreck-it Ralph shows a Teenage Mutant Ninja Turtles arcade machine, and the Teenage Mutant Ninja Turtles have a comic book crossover with Batman. Scooby Doo and the Mystery Gang show up in an episode of Batman. Scooby Doo, of course, has a crossover with Johnny Bravo. Johnny Bravo is in an obscure Smash Bros. ripoff for the Wii, called Cartoon Network: Punch Time Explosion. All three Powerpuff Girls show up in this game. Therefore, my conclusion here is that Fortnite does in fact take place in the same universe as The Powerpuff Girls.